Homeopathy’s role and value to address antimicrobial resistance

ECH – SSH conference: Homeopathy’s role and value to address antimicrobial resistance – Online access to the articles

Dr Hélène RENOUX – ECH president

Pr Leoni Bonamin – Paulista University (Sao Paulo)

Pr Jennifer Jacobs – University of Washington

Pr Francesco Macri – La sapienza University (Rome)

Dr Liesbeth Ellinger – The Netherlands

Dr Lex Rutten – The Netherlands

Dr Katharina Gaertner – Wisshom

Dr Bernard Poitevin – SSH

Homeopathy outraged by fake news

Our Belgian Association UNIO has published the following statement:

Homeopathy outraged by fake news

Users of homeopathic medicines can no longer remain silent about the untruths circulating in the media. These lies raise doubts which naïve and gullible people take on board all too easily and then see homeopathy as quackery. None of this is accurate!

Because they fear seeing some of their ‘certainties’ questioned, the SKEPP movement is firing off at anything that current science cannot yet explain with both barrels.

The contents of homeopathic medicines
SKEPP states that a homeopathic medicine is nothing more than a drop of water in a swimming pool and therefore has nothing in it. This is  wrong. Tests performed on a high homeopathic potency (30CH) of Gelsemium sempervirens (Yellow Jasmine, a very common homeopathic medicine) have detected 36 micrograms of a specific substance per gram of solution [1]. Opponents denounce homeopathic medicines as being nothing but water. This is  wrong. This water, the solvent itself, contains a specific signature of the active ingredient. Basic research has demonstrated this [2].

Clinical efficacy.
By asserting at every opportunity that there is no evidence of the clinical effectiveness of homeopathy, opponents sow doubt. Correction:  such proof [3] does exist.  The fact that critics refuse to look at or accept these data speaks volumes about their attitude to science.
What is true, however, is that there is  not enough  scientific evidence of effectiveness. Science demands a lot of such evidence – and rightly so. There would be more if the universities applied the rules correctly!  For example: The Professional Union of Homeopathic Physicians had accepted a double-blind research protocol for fibromyalgia which took account of homeopathy’s individualized approach. This research was to be carried out at the Rheumatology Department of a hospital in Brussels with the agreement of the Rector of the Faculty of Medicine. But the hospital’s ethics committee decided that it would be unethical to test a ‘placebo’ (the homeopathic medicine) versus another placebo! Making an a priori assumption that homeopathic medicine is just a placebo, even before beginning the study, flies in the face of scientific objectivity.

Patients are not stupid!
In the meantime, Pro Homeopathia, the Belgian association of homeopathy patients, is no longer able to contain its members’ exasperation. It has published an article [4]  which denounces in direct terms the accusations of credulity, or even stupidity levelled at patients, in blatant disregard of their therapeutic freedom of choice and their capacity for critical thought.

Dare to ask questions! 
Why all this misinformation in the press? Why do these ‘experts’, whose opinions on homeopathy above all betray their profound misunderstanding of this discipline, flood the media with fake news? What is the hidden agenda behind this campaign of systematic denigration? Homeopathy and many other complementary medicines only want to collaborate, both in medical practice and in scientific research … fair play! It’s called integrative medicine!

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References
[1]Nanoparticle Characterization of Traditional Homeopathically-Manufactured Cuprum metallicum and Gelsemium Sempervirens Medicines and Controls. Novembre 2018: https://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1666864)
[2]Nuclear Magnetic Resonance characterization of traditional homeopathically-manufactured copper (Cuprum metallicum) and a plant (Gelsemium sempervirens) medicines and controls. Août 2017: https://doi.org/10.1016/j.homp.2017.08.001
[3]Model validity and risk of bias in randomized placebo-controlled trials of individualised homeopathic treatment. 2016: http://dx.doi.org/10.1016/j.ctim.2016.01.005 //Clinical verification in homeopathy and allergic conditions. 2012 http://dx.doi.org/10.1016/j.homp.2012.06.002 //Scientific framework of homeopathy 2017. www.lmhi.org/Article/Detail/42)
[4]http://www.homeopathie-unio.be/uploads/files/unprotected/Presse/Attaques%20Hom%C3%A9o-FR2.pdf

Media coverage of the Sofia Symposium

The Symposium “Homeopathy in the 21st Century”, jointly organised by ECH, IAVH and the Association of Homeopathic Physicians in Bulgaria, was a great success. It was attended by more than 400 medical doctors, veterinarians and pharmacists from 27 countries.


The lectures and presentations discussed the integration of conventional and homeopathic medicine and showed practical examples. Dr Gheeta Krishnan Gopalakrishna Pillai, Technical Officer at the Traditional, Complementary, and Integrative Medicine Unit at the World Health Organization presented the WHO Traditional Medicine Strategy 2014-2023.

The Symposium that took place in Sofia on 17 and 18 November was preceded by Workshops on Research and Provings, a Veterinarian Seminar and the ECH General Assembly. The General Assembly elected Dr Tiziana di Gampietro as new Research Coordinator and re-elected Dr Sara Eames, as Vice-president, Dr Arlette Blanchy, as Treasurer and Dr Ilse Muchitsch, as Pharmacy Coordinator.

The press conference attracted many journalists from both the health and mainstream press. The Bulgarian media published interviews with Dr Raj K. Manchanda, Director General of the Central Council for Research in Homeopathy of India, Dr Hélène Renoux, ECH President, Dr Edward de Beukelaer, IAVH President and Dr Sigrid Kruse from the University Children’s Hospital in Munich.

Some examples of the media coverage can be accessed using the links below. We have also provided a translation of two of the articles.

1. From http://new.zdravennavigator.bg/index.php?option=com_content&view=article&id=24718:vseki-treti-v-evropa-se-doveryava-na-homeopatiyata&catid=8:novini

Homeopathy can help fight the growing problem of antibiotic resistance. The timely use of homeopathic remedies reduces the need for antibiotics, and so they can be preserved where they are really needed. This is what Dr. Hélène Renoux, President of the European Committee for Homeopathy declares. Together with leading homeopaths from all over the world, she participated in the first International Homeopathic Symposium in Bulgaria.

Evidence for the popularity of homeopathy can be seen by the fact that more and more Europeans choose it. About 30% of Old Continent residents are treated with homeopathic remedies, and over 45,000 doctors have been trained and used daily in their practice. By integrating the method into pre-hospital and hospital care, we can enjoy quality improvement in healthcare services, reduce the length of hospitalizations, and the cost of treatment, “Dr. Renoux adds.

A study in France (EPI3), for example, shows that patients with family doctors who offer homeopathy, use significantly less antibiotics in upper respiratory tract infections. The same study states that total healthcare spending is 20% less for patients who consult with homeopathic doctors. This finding has also been confirmed by a number of other studies, as well as other benefits such as the lack of undesirable side effects in homeopathic treatment.

Statistics on antibiotic resistance are startling. 33 000 deaths in the EU per year, and around 700 000 worldwide. In practice, antibiotics cannot deal with all bacterial strains. The resistance of Escherichia coli, for example, to major preparations increases in almost all countries in Europe. The situation worsens with the emergence of new bacterial strains resistant to several antibiotics (multi-resistant bacteria). We risk living in a world where organ transplants, chemotherapy and other medical procedures could become impossible. A banal bacterial infection can become a threat to our lives.

That’s why homeopathy’s potential is appreciated in more and more countries. It is the second most common medical therapy in Europe and worldwide. In the UK, Romania, Hungary, Belgium, Bulgaria and Slovenia, there are special laws regulating its use. In France, Belgium, Latvia, Switzerland and some areas of the United Kingdom homeopathic treatment is covered by compulsory health insurance. Homeopathic learning, as an additional qualification, is available in many universities and private schools in Europe.

In Bulgaria, homeopathic treatment can only be applied by doctors. Approximately 3000 medics integrate various alternative methods of treatment, including homeopathy their practice. Nearly 2,500 of them have completed a course in homeopathy. Physician homeopaths, practicing mainly homeopathic therapy number about 200, explains Dr. Dora Pachova, chairman of the Association of Homeopathic Doctors in Bulgaria. The fact is that more and more doctors are interested in the method because they see positive results in their patients. Medical professionals who are guided by evidence based medicine in their clinical practice are also inclined to include homeopathic therapy in their treatment recommendations when there is adequate evidence for its use.

In veterinary medicine homeopathy is gaining increasing popularity. There are already successful homeopathic veterinary clinics and centers around the world, and these are now starting up in Bulgaria. People who are interested in the use of homeopathy are becoming more and more interested not only in their own treatment, but also in their pets as well as in livestock farming because of the products we consume, said Dr. Eduard de Bökkelar, president of the International Association of Veterinary Homeopathy.

2. https://www.vesti.bg/sviat/germanski-lekar-homeopatiiata-mozhe-da-pomaga-6088936

Dr. Sigrid Kruse is a physician pediatrician, working in the Department of Integrative and Rehabilitation Pediatrics at Dr. von Hauner Children’s Hospital, Ludwig-Maximilian University in Munich, Germany. Dr. Kruse was a guest at the International Homeopathic Symposium, which took place in Sofia from 15 to 18 November.

She says she has begun to work with homeopathy because her goal as a doctor was to get the best possible treatment for each patient. According to Dr. Sigrid Kruse, homeopathy has a place in modern pediatrics precisely because it is so important to find the best therapy for each child in hospital.

At the Children’s University Hospital in Munich, homeopathy is used as an accompanying treatment for severely ill children, where the possibilities of conventional treatment are unsatisfactory. Dr. Kruse said that since the beginning of the project, even the biggest skeptics in the hospital have changed their attitude.

In practice, every homeopathic medicine can be prescribed and offered on the principles of classical homeopathy. Very often the parents themselves want this therapy for their child as an accompanying treatment. More than 1,000 patients per year receive complementary homeopathic treatment in the hospital.

Since 2002, the National Health Insurance System in Germany has financially supported homeopathy at this university hospital. In addition to homeopathic treatment, there are also scientific studies to help determine the benefit of complementary homeopathic therapy for enuresis, recurrent urinary tract infections, brain haemorrhages in neonates, withdrawal in newborns (children of drug addicts), and more.

“The point is not to cut conventional medicine at the expense of homeopathy or to argue which method is better. The point is choosing the best and most appropriate treatment for the patient”, Dr. Kruse said. “We have to keep in mind that homeopathy is a therapy that stimulates and regulates the processes in the body, so we know where the benefits are and where the limitations are in applying this. By following these principles, we get very good results at our hospital”, she says.

In the hospital, homeopathy was also used in neonatal care, in cases of increased restlessness in babies, because it is not good to use sedatives. One of these examples is Kevin. When he was three, he wept fretfully, and he has to have an encephalogram. The mother was addicted to heroin and the child was born with withdrawal syndrome. After birth, Kevin had an epileptic attack, after which he was extremely restless and did not stop crying. “I decided to try homeopathy and I applied homeopathic remedy Opium in high dilution.” The baby relaxed and fell asleep – as if we had “turned off the button,” says the pediatrician.

Germany is one of the European countries where homeopathy traditionally enjoys high popularity with around 7000 homeopathic doctors. There are about 3000 medical practitioners integrate various alternative methods of treatment, including homeopathy in their practice in Bulgaria. Nearly 2,500 of them have completed a course in homeopathy.

3. 6br_Medicart_2018

4. Zdraven jurnal_11_2018

5. 20112018_Jult Trud_47_036

6.

7.

8. https://www.credoweb.bg/publication/110894/vseki-treti-v-evropa-se-doveryava-na-homeopatiyata?fbclid=IwAR194b-Tl2mldWhq3D9u8IDIfbX6bShY7DASGc5vXz4QSuLNIe97L0eG9Js

9. https://www.puls.bg/khomeopatiia-c-18/d-r-elen-renu-khomeopatiiata-e-bdeshcheto-na-meditsinata-n-32652

10. http://zonazdrave.com/index.php?option=com_content&task=view&id=2588&Itemid=45

11. https://mamamia.bg/izvan-gnezdoto/homeopatiyata-li-e-reshenieto-na-problema-s-antibiotichnata-rezistentnost/

Flawed Research Used to Discredit Homeopathy

The recent statement by the European Academic Science Advisory Council (EASAC) concludes that there is no scientific evidence for efficacy of homeopathy which is based on three flawed research studies. Moreover, the statement has not reviewed the numerous studies that show positive outcomes for homeopathy. This selection bias seriously undermines EASAC claims that its conclusions are based on “excellent science based assessments”.
The EASAC statement is based on:

  • The 2010 House of Commons Science and Technology Committee’s report on homeopathy, which was rejected by the UK government and an Early Day Motion was signed by 70 MPs unhappy at the way the committee conducted its review.
  • The Australian National Health and Medical Research Council’s (NHMRC) 2015 review of homeopathy, which is under investigation by the Commonwealth Ombudsman for the numerous irregularities in the way it conducted this review.
  • The 2005 Shang review, which reported to have compared 110 similar trials on homeopathy and conventional medicine, and reached the conclusion that homeopathy is no better than placebo. However, the conclusions of this study were in fact based on only eight of the 110 trials, none of which involved usual homeopathic care.

The EASAC working group that produced the statement did not include a single expert on homeopathic research. On the other hand, one member of the working group has been the former chairman of a national sceptic’s association. This is in contradiction with EASAC’s claim that the statement was produced by “authoritative and impartial bodies”.
Therefore, this statement from EASAC cannot be used to inform policymaking in such an important area as the right of European citizens to choose their health care options. 

For more information about the evidence, research and common misperceptions around homeopathy, visit the website of the Homeopathy Research Institute (HRI)

1. https://www.hri-research.org/resources/essentialevidence/

2. http://www.parliament.uk/edm/2009-10/908
3. https://www.hri-research.org/resources/homeopathy-the-debate/the-australian-report-on-homeopathy/

4. https://www.hri-research.org/resources/homeopathy-the-debate/the-lancet-paper-by-shang-et-al/

HOMEOPATHIC SOLUTIONS HAVE MEMORY

A team of Belgian scientists, leaded by Michel Van Wassenhoven, has demonstrated a memory effect of homeopathic solutions. The researchers identified the signature of Cuprum metallicum and Gelsemium sempervirens, even in the highest dilution, using Nuclear Magnetic Resonance relaxation times’ measurements.

They state that the existence of an Avogadro’s “wall” for homoeopathically prepared medicines is not supported by their data. They consider that all dilutions have a specific material configuration determined by the potentized substance, the chemical nature of the containers, dissolved gasses and the electromagnetic environment. The researchers conclude that the time is now ripe for a demystification of the preparation of homeopathic remedies.

For more information…

To those who demand scientific evidence for homeopathy *

Marcus Zulian Teixeira**

Upon discussing homeopathy in various settings, we often find that people react with mistrust, raise doubts about its scientific grounds and therapeutic validity. Widely disseminated in the mass media, in an indistinct and reiterated manner, the fallacy – or post-truth – asserting “there is no scientific evidence for homeopathy” is incorporated into the collective subconscious, which thus serves as strategy to increase prejudice and radicalize postures against this bicentennial medical approach.

A fruit of disinformation or of negation of the studies that provide grounds to the homeopathic paradigm in many scientific fields, prejudice is once and again fed by unfavorable pieces published in mass media and social networks, which, in turn, very seldom divulgate studies with results favorable to homeopathy.

To elucidate doctors and society at large in this regard and to demystify culturally rooted dogmatic attitudes, the Technical Chamber for Homeopathy, Regional Medical Council of the State of São Paulo (CREMESP, Brazil), prepared Special Dossier, “Scientific Evidences in Homeopathy”. This project had the support of the Brazilian Homeopathic Medical Association (AMHB) and the São Paulo Homeopathic Medical Association (APH) via divulgation in its scientific journal, Revista de Homeopatia.

In addition to describing the global situation of homeopathy as a medical specialty and its inclusion in the curricula of medical schools, the dossier further includes reviews on research lines that provide grounds to the homeopathic assumptions, to wit: therapeutic similitude, homeopathic pathogenetic trials, serial and agitated dilutions (high dilutions – HDs), and individualization based on the set of characteristic symptoms exhibited by patient/disease. Similarly, the efficacy and safety of homeopathic treatment are demonstrated in randomized, placebo-controlled clinical trials, systematic reviews and meta-analyses.

The dossier begins by a review entitled “Homeopathy: a brief description of this medical specialty”, which discusses historical, social and political aspects of the institutionalization of homeopathy in Brazil and its inclusion in health care systems. It further describes the reasons for patients to seek this therapeutic approach.

The review on “Medical education on non-conventional therapeutics in the world (homeopathy an acupuncture)” highlights the relevance of the inclusion of homeopathy and acupuncture in the curriculum of medical schools in many countries around the world. Such inclusion – actualized in various modalities specifically targeting undergraduate and graduate students, medical residents and practicing doctors – is a result of the increasing interest of patients, leading to a similar interest among doctors to learn about such medical approaches.

Looking to providing scientific grounds to the therapeutic similitude principle through systematic study of the rebound effect of modern drugs, the review entitled “Scientific basis of the homeopathic healing principle in modern pharmacology” discusses hundreds of studies published in high-impact scientific journals and that demonstrate a conceptual and phenomenological similarity between rebound effect and the vital reaction (or secondary action) that homeopathic treatment elicits. Aiming at broadening the implications of such similarity, the author describes the use of modern drugs according to the therapeutic similitude principle, which leads to the application of the rebound effect (paradoxical reaction of the organism) with curative intention.

To account for the plausibility of the homeopathic use of HDs, the present dossier includes three reviews that describe the advances made in fundamental research along the past decades: “The soundness of homeopathic fundamental research”, “Effects of homeopathic high dilutions on in vitro models: literature review”, and “Effects of homeopathic high dilutions on plants: literature review”. These reviews discuss hundreds of experiments and dozens of lines of research that together demonstrate the effects of HDs in physical-chemical and biological models (in vitro, plants and animals).

Demonstrating that the positive effects of homeopathic treatment are not mere placebo effect, as it is widely advertised, review “Clinical research in homeopathy: systematic reviews and randomized clinical trials” describes the positive results found in dozens of homeopathic placebo-controlled clinical trials targeting variable clinical conditions, as well as systematic reviews and meta-analyses. These results are particularly illustrated by two clinical trials conducted at prestigious Brazilian research institutions: “Potentized estrogen in homeopathic treatment of endometriosis-associated pelvic pain: a 24-week, randomized, double-blind, placebo-controlled study” and “Randomized, double-blind trial on the efficacy of homeopathic treatment in children with recurrent tonsillitis”.

As concerns the safety of homeopathic treatment, the review entitled “Do homeopathic medicines cause drug-dependent adverse effects or aggravations” demonstrates, through an analysis of placebo-controlled clinical trials, that although mild and transient, homeopathic medicines cause more adverse effects compared to placebo.

The final review, “Do homeopathic medicines induce symptoms in apparently healthy volunteers? The Brazilian contribution to the debate on homeopathic pathogenetic trials” discusses the historical development and the state of the art in homeopathic pathogenetic experimentation. These experiments are conducted to establish the curative properties of drugs (pathogenetic effects in health individuals) that ground the application of the therapeutic similitude principle.

Despite the ongoing difficulties and limitations opposing the development of research in homeopathy – partly due to methodological aspects, and partly to lack of institutional and financial support – the experimental and clinical studies described in this dossier, which ground the homeopathic assumptions and confirm the efficacy and safety of this approach to therapeutics – provide unquestionable proof for the “availability of scientific evidences for homeopathy”, against the false and prejudiced opinion that is widely divulgated. Nevertheless, further studies are still needed to improve clinical practice and elucidate some aspects peculiar to the homeopathic paradigm.

With the divulgation of the present dossier, prepared with the support of Technical Chamber for Homeopathy, CREMESP, we hope to dispel doubts and sensitize our colleagues as to the validity and relevance of homeopathy as adjuvant treatment complementary to all other medical specialties according to ethical and safe principles. Our overall goals are to broaden the understanding of human disease, increase the therapeutic resources, contribute to the definition and effectiveness of medicine in chronic diseases, minimize the adverse effects of modern drugs and strengthen the patient-doctor relationship, among other aspects. In this way, we will be able to work together, since “The physician’s high and only mission is to restore the sick to health, to cure, as it is termed (Samuel Hahnemann, Organon of medicine, § 1).

*Translation of: Teixeira MZ. Editorial: Aos que clamam pelas evidências científicas em homeopatia. Revista de Homeopatia (São Paulo). 2017; 80(1/2): i-iii. Disponível em: http://aph.org.br/revista/index.php/aph/article/view/402/450.

**Marcus Zulian Teixeira

MD, BC Homeopathy; PhD, Medical Sciences; Professor of “Fundamentals of Homeopathy”, School of Medicine, University of São Paulo; Member of Technical Chamber for Homeopathy, Regional Medical Council of the State of São Paulo (CREMESP, Brazil).

Global Demand for Homeopathy Forecast to Surge

The growth in demand for homeopathic products is set to increase significantly over the course of the next few years. According to research by US-based Transparency Market Research, growing interest in homeopathy in developed countries has fueled the growth in the homeopathic products market, which is forecast to reach over $17bn by 2024 – the same market was calculated to be worth $386m in 2015.

Whilst the Middle East and Africa and Asia Pacific regions are set to produce the largest growth, due to increased disposable income and greater availability of products online respectively, it is anticipated that Europe will remain the largest market throughout this period. Mustard Research’s 2015 consumer research report found that 9 million people in the UK use homeopathic products and TMR’s report suggests that there is no sign of its popularity diminishing, as more holistic forms of treatment are favoured and credible alternatives to over-prescription are sought.

Profiles of the major homeopathic manufacturers – Boiron Group, Biologische Heilmittel Heel GmbH, A Nelson & Co Ltd, GMP Laboratories of America, Inc., Standard Homeopathic Company (Hyland’s, Inc.), Washington Homeopathic Products, Inc., Homeocan inc., Hahnemann Laboratories, Inc., Mediral International Inc., and Ainsworths Ltd – are included in the report.

Homeopathy provides safe, gentle treatment for many conditions and can address many of the serious threats faced by the global population. Antimicrobial Resistance (AMR) is one such threat, which is attributed to the overuse and misuse of antibiotics, where in many cases homeopathy is known to be an effective alternative. For example, clinical research suggests that homeopathy is effective in the treatment of upper respiratory tract infections in children, a frequent cause of inappropriate antibiotic prescribing.

The aim of the ECH is to achieve full integration of homeopathy within the European healthcare system, which will meet the growing demand, specifically of European citizens, for homeopathic care within a safe medical context so the findings of this report are welcomed.

To request a sample of this report, please visit http://www.transparencymarketresearch.com/sample/sample.php?flag=S&rep_id=16460

Homeopathy Journal consolidates its scientific status

The journal Homeopathy, published by the UK Faculty of Homeopathy, a member of ECH, has been given an impact factor (IF) for 2017 of  1.16, an increase of more than 50% on its previous assessment. An IF is used to determine the impact a particular journal has in a given field of research by measuring how many times on average articles published in that journal have been cited by other articles, and is therefore widely used as a measure of quality.

This is an acknowledgement not only of the quality of the journal Homeopathy but also of the quality of current research in homeopathy.

Published quarterly, Homeopathy is an international journal that aims to improve the understanding of clinical practice of homeopathy by publishing high quality articles on clinical and basic research, clinical audit, evidence-based practice of homeopathy and reflective case reports. It regularly features research and articles from many of the foremost scientists and practitioners currently working in homeopathy.

Homeopathy is available to all members of the UK Faculty of Homeopathy and by subscription from Elsevier www.elsevier.com and online at www.homeopathyjournal.net

Homeopathy to continue to be included in Swiss National Health Insurance

The Swiss Federal Government has announced that medical services using complementary medicine, including homeopathy, will continue to be covered by national health insurance. This decision has been taken following a two year trial period and acknowledges that complementary medicine in Switzerland meets statutory regulations when it comes to effectiveness, guaranteeing high quality and safety.

As of 1 August 2017, anthroposophical medicine, classical homeopathy, traditional Chinese medicine and herbal medicine will be fully covered by mandatory health insurance (basic insurance), provided that these are practised by conventional medical practitioners who have an additional qualification in one of the four disciplines as recognised by the Swiss Medical Association (FMH).

This is very positive news and a decision that is welcomed by the European Committee for Homeopathy, which is committed to integrating high-quality homeopathy into European healthcare and supports all medical doctors with an additional qualification in homeopathy in 25 European countries.

Click here to view the press release from the Union of Associations of Swiss Physicians for Complementary Medicine.